CN / EN

Your current location : 首 页 >> News >> Technical Information

ContactContact Us

Yingkou Liaobin Fine Chemical Co., Ltd.

Sales Department:

Telephone: 15940764666

                   18340783333

Landline: 0417-3902111

Ministry of Foreign Trade:

Landline: 0417-3902444

Fax: 0417-3902118

Mail box: 75007001@qq.com

Address: No. 517, Xiangyang Chemical Industry Park, Laobian District, Yingkou City, Liaoning Province

Website: www.yklbhg.com

No side effects: Boron nitride nano film can replace antibiotics for antibacterial

2021-08-01 10:08:23
a

A few days ago, the Russian National University of Science and Technology (NUST-MISIS) published a research result in the ACS Journal of Applied Materials and Interface. They developed an antibacterial nano-coating based on boron nitride, which is very effective against microbial pathogens (up to 99.99%). With high efficacy and no obvious side effects, it can be used to replace antibiotics in implant surgery. Boron Nitride


Surgery, especially orthopedic and dental operations, implants are likely to introduce microorganisms and cause infections. Antibiotics are a must, but high doses of antibiotics can bring side effects. Researchers at NUST-MISIS found through research that the boron nitride nano-film coating killed 100% of Gram-negative bacteria and E. coli in 24 hours. "Hexagonal boron nitride has unique physical, chemical and mechanical properties. The experimental results show that the special structure of boron nitride nanoparticles provides a bactericidal effect equivalent to antibiotics: the death of bacteria is due to direct physical contact with the special needle-like surface of the nano film And dead.” explained Christina Gudz, a researcher at the Inorganic Nanomaterials Laboratory.

The researchers further filled the micropores with a thin layer of boron nitride coating with gentamicin antibiotics. Since the drug is completely released in a short time, it produces an antibacterial effect. Moreover, its dose is an order of magnitude smaller than conventional injections. "Considering that the patient’s average weight is 60 kg, his daily antibiotic dose is about 180 mg; assuming that the implantation area is 30 square centimeters, and considering that the nano coating in the study releases 55 micrograms of antibiotics, the results show that The proposed method assumes that antibiotics are 100 times less "injected" than standard drugs," Christina Gudz added.


At present, the team is completing in vitro research on the obtained coating and is optimizing the coating method in order to achieve practical applications in the future.


Sales
Sales Department

Telephone: 15940764666

Landline: 0417-3902111

Website: www.yklbhg.com

Address: No. 517, Xiangyang Chemical Industry Park, Laobian District, Yingkou City, Liaoning Province

foreign
foreign trade Department

Landline: 0417-3902444

Fax: 0417-3902118

Mail box: 758007001@qq.com

Address: No. 517, Xiangyang Chemical Industry Park, Laobian District, Yingkou City, Liaoning Province

Copyright © Yingkou Liaobin Fine Chemical Co., Ltd. All rights reserved :